Hotel S. Anna
Borgo Pio 133, Rome, Lazio, 00193, Italy
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Borgo Pio 133, Rome, Lazio, 00193, Italy
Just 220 yards from St Peter’s Basilica, Sant’Anna Hotel is a 17th-century building offering elegant rooms and interiors in central Rome. Wi-Fi is free and a varied continental breakfast is available. With coffered ceilings and refined furniture, rooms have a classic-style atmosphere. They are air conditioned and feature an LCD TV and a safe. Just 435 yards from Castel Sant’Angelo, Hotel Sant’Anna is less than a 10 minute walk from Ottaviano Metro Station. The Spanish Steps are only 3 Metro stops away. License Number(s): 058091-ALB-00380, IT

Hotel Services and Facilities

Free WiFi Free parking Free breakfast Pet friendly

Hotel facilities

  • Garden
  • Room Service
  • Safety Deposit Box
  • Air Conditioning
  • 24-Hour Front Desk
  • Express Check-In/Check-Out
  • Elevator
  • Heating
  • Private check-in/check-out
  • Concierge services
  • Family Rooms
  • Free Wi-Fi
  • Daily Housekeeping
  • Non-Smoking Rooms Available
  • Outdoor furniture
  • Key access
  • Smoke alarms
  • Fire extinguishers
  • Staff follow all safety protocols as directed by local authorities
  • Shared stationery such as printed menus, magazines, pens, and paper removed
  • Process in place to check health of guests
  • First aid kit available
  • Cashless payment available
  • Linens, towels and laundry washed in accordance with local authority guidelines
  • Hand sanitizer in guest accommodation and key areas
  • Invoices
  • All plates, cutlery, glasses and other tableware have been sanitized
  • Access to health care professionals
  • Food delivery
  • Audible alarm
  • Daily disinfection
  • Luggage storage & lockers
  • Non-smoking property
  • Restaurant (special diets available)
  • Physical/social distancing guidelines
  • Protective screen or physical barriers in appropriate areas
  • Professional cleaning services
  • Takeout dining services available
  • Airport shuttle (charges may apply)
  • Shuttle service (charges may apply)
Click here to leave your opinion >>
stayed in March, 2026
Guest Score 9 out of 10
Wonderful
stayed in March, 2026
Guest Score 8 out of 10
Very Good
An elegant, unfancy and most welcoming independent hotel - perfect for a couple of nights for work or holidaying. A stone's throw from Castel St Angelo and the Vatican. Simple, delicious breakfast.
stayed in March, 2026
Guest Score 9 out of 10
Wonderful
Very nice room, comfortable, with a balcony and a big bathroom. Great location. The hotel is close to the Vatican and the Castel Sant Angelo, but the area around it was never too crowded.
Generally I was very satisfied. I wasn't a big fan of the breakfast, but it is possible to pick up something on the go from many places around. The hotel is also a bit too expensive.
stayed in March, 2026
Guest Score 10 out of 10
Exceptional
Everyone there was so nice and helpful! Everything was clean and comfortable. It was on a beautiful street and in a central location just minutes from the Vatican. I really loved the staff, they were very kind and welcoming
Honestly I loved everything, I have no complaints
stayed in February, 2026
Guest Score 9 out of 10
Wonderful
Location is excellent, quiet street, small hotel, breakfast was excellent, staff very friendly.
Lift is small but we didn’t need.
stayed in February, 2026
Guest Score 10 out of 10
Exceptional
Excellent location, friendly staff !
stayed in January, 2026
Guest Score 8 out of 10
Very Good
Location Staff Cleaning
stayed in January, 2026
Guest Score 10 out of 10
Exceptional
Elizabeth and Marcello were outstanding front desk staff! They were super helpful. The breakfast was delicious and the hotel and room were kept very clean. The location was excellent and a safe area for solo travelers.
My only comment here is that the shower floor was very slippery and the provided soap made it even more difficult. Some type of non-slip mat needs to be provided to keep guests safe from falling.
stayed in January, 2026
Guest Score 8 out of 10
Very Good
Great location ! 2 minute walk to the Vatican. Hotel staff was great. Breakfast was awesome. Rooms very clean and well maintained.
stayed in January, 2026
Guest Score 10 out of 10
Exceptional
I like the neighborhood and the small, charming atmosphere. Staff is always most pleasant. I’ve stayed here many times and hope to return…
I can’t complain. Some would consider the furnishings a bit worn, but I overlook that for the charm of the place.
stayed in January, 2026
Guest Score 10 out of 10
Exceptional
I like the neighborhood and the small, charming atmosphere. Staff is always most pleasant. I’ve stayed here many times and hope to return…
I can’t complain. Some would consider the furnishings a bit worn, but I overlook that for the charm of the place.
stayed in December, 2025
Guest Score 8 out of 10
Very Good
Location
stayed in December, 2025
Guest Score 8 out of 10
Very Good
Location
stayed in December, 2025
Guest Score 10 out of 10
Exceptional
stayed in December, 2025
Guest Score 10 out of 10
Exceptional
The location was wonderful! Near the Vatican which was very convenient for our early morning skip the line tour. The street was quiet at night which made for a lovely night’s sleep. The staff was very friendly and helpful with tips and recommendations. The rooms are a nice size for Europe and the beds and pillows were comfy. The hotel breakfast was good…wonderful coffee!
stayed in December, 2025
Guest Score 10 out of 10
Exceptional
The location was wonderful! Near the Vatican which was very convenient for our early morning skip the line tour. The street was quiet at night which made for a lovely night’s sleep. The staff was very friendly and helpful with tips and recommendations. The rooms are a nice size for Europe and the beds and pillows were comfy. The hotel breakfast was good…wonderful coffee!
stayed in December, 2025
Guest Score 10 out of 10
Exceptional
stayed in November, 2025
Guest Score 10 out of 10
Exceptional
stayed in November, 2025
Guest Score 10 out of 10
Exceptional
stayed in November, 2025
Guest Score 9 out of 10
Wonderful
The beds & good bathroom shower … staff were very attentive & professional ! Breakfast was simple & right variety .
The wardrobe hanging bar was high & the hangar type offered were not suitable .
Guest reviews
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Availability from Sat, Apr 4, 2026 To Tue, Apr 7, 2026 For 1 Room (Change Search)
Room type
Max
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Rate
Economy Double Room
Providing free toiletries, this double room includes a private bathroom with a bath or a shower, a bidet and a hairdryer. the air-conditioned double room provides a flat-screen tv with satellite channels, a mini-bar, a tea and coffee maker, a wardrobe as well as an inner courtyard view. the unit offers 1 bed.
2 x
Free cancellation
Free WiFi
$316.88USD
Average nightly rate
Book Now
Monday
Tuesday
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Thursday
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Saturday
Sunday
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$316.88
$316.88
$316.88
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Average nightly rate $316.88 Total (including tax) $1,087.55
2 x
Free cancellation
Free breakfast
Free WiFi
$333.56USD
Average nightly rate
Book Now
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
-
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$333.56
$333.56
$333.56
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Average nightly rate $333.56 Total (including tax) $1,142.60
  • Accessible by lift
  • Air conditioning
  • Bath or Shower
  • Bidet
  • Body soap
  • City view
  • Closet
  • Coffee/tea machine
  • Courtyard view
  • Desk
  • Electric kettle
  • Emergency cord in bathroom
  • Flat-screen TV
  • Hair dryer
  • Hand sanitiser
  • Hardwood or parquet floors
  • Heating
  • Hypoallergenic
  • In-room safe box
  • Individual air conditioning
  • Key access
  • Linens
  • Mini bar
  • Non-feather pillow
  • Phone
  • Private bathroom
  • Satellite/cable channels
  • Shower cap
  • Smoke alarm
  • Socket near the bed
  • Toilet
  • Toilet paper
  • Toiletries
  • Towels
  • Trash cans
  • TV
  • Upper floors accessible by elevator
  • Wake-up service
View more >>

Area information

    Airports Show all on map »

    • Rome Ciampino Airport - 10.04 mi
    • Leonardo Da Vinci - Fiumicino Airport - 12.34 mi

    Attractions/Entertainment

      Zoo Show all on map »
      • Vatican Gardens - 275 f

    Museums

      Art Galleries Show all on map »
      • Museo Storico dell'Arma dei Carabinieri - 0.22 mi
      • Vatican Museum - 0.33 mi
      • Vatikanische Museen - 0.34 mi
      • Castel Sant'Angelo Museum - 0.37 mi

    Hospitals

      Hospitals Show all on map »
      • Santo Spirito General Hospital - 0.33 mi
      • Bambino Gesu Pediatric Hospital - 0.44 mi

    Transport

      Train stations Show all on map »
      • Vatican Railway Station - 0.46 mi
      • Stazione di San Pietro - 0.47 mi

    Other attractions

      Monuments and Landmarks Show all on map »
      • Porta Angelica - 476 f
      • Fontana delle Tiare - 520 f
      • Via della Conciliazione - 730 f
      • Statua di Santa Caterina - 0.26 mi
      • Borgo - 0.31 mi
      • The Vatican - 0.33 mi
      • Monument to Alexander VII - 0.33 mi
      • Ponte Vittorio Emanuele II - 0.36 mi
      • Statua di S. Michele - 0.38 mi
      • Ponte S. Angelo - 0.41 mi
      • Statue of St Michele - 0.42 mi
      • Fontana di Piazza dei Quiriti - 0.48 mi
      • Piazza Cavour - 0.48 mi
      • Legulei - 0.48 mi
      Golf Courses Show all on map »
      • Country Club Castelgandolfo - 940 f
      Historical Buildings Show all on map »
      • Saint Peter's Cathedral - 0.25 mi
      • Sant'Angelo Castle - 0.36 mi
      • Castel Sant'Angelo - 0.38 mi
      Rivers and Lakes Show all on map »
      • Tiber River - 0.43 mi
      Other Show all on map »
      • Piazza Pio XII - 591 f
      • Basilica di San Pietro - 642 f
      • St Peters Square Piazza San Pietro - 815 f
      • Piazza di San Pietro - 815 f
      • St Peter s Basilica Basilica di San Pietro - 955 f
      • The Vatican - 956 f
      • Vatican area - 956 f
      • Belvedere Courtyard - 0.24 mi
      • Palazzo Serristori - 0.27 mi
      • Pigna Courtyard - 0.28 mi
      • St Peter Enthroned - 0.33 mi
      • Vatican Grottoes - 0.33 mi
      • Sistine Chapel Cappella Sistina - 0.33 mi
      • Teatro Ghione - 0.37 mi
      • San Giovanni Battista dei Fiorentini - 0.38 mi
      • Ottaviano - San Pietro - 0.41 mi
      • Il Borgo - 0.43 mi
      • Rome Illuminated - 0.45 mi
      • Via dei Banchi Nuovi - 0.49 mi
      • Via dei Banchi Vecchi - 0.53 mi
      • Palazzo di Giustizia The Hall of Justice - 0.54 mi
      • Trionfale Market - 0.55 mi

Hotel S. Anna

Borgo Pio 133, Rome, Lazio, 00193, Italy